STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
txnThioredoxin; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
txnipa
Thioredoxin-interacting protein a.
   
 0.999
txnipb
Thioredoxin-interacting protein b.
    
 0.994
txn2
Thioredoxin 2.
  
0.973
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 
 0.962
txnrd3
Thioredoxin reductase 3.
  
 
 0.952
gsr
Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.916
prdx2
Peroxiredoxin 2.
  
 
 0.910
TXN
Thioredoxin; Belongs to the thioredoxin family.
  
 
 
0.902
gpx1a
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.900
gpx7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.895
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.