STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mafaaTranscription factor MafAa; Transcription factor, possibly involved in transcription regulation during lens development, including that of crystallin genes. Specifically binds to the alphaCE2 enhancer element of crystallin gene. (315 aa)    
Predicted Functional Partners:
pdx1
Pancreatic and duodenal homeobox 1.
   
 
 0.760
ttpal
Tocopherol (alpha) transfer protein-like.
      
 0.740
fosab
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 
 0.682
ppp1r2
Protein phosphatase 1, regulatory (inhibitor) subunit 2.
      
 0.567
ins
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.500
pax4
Paired box 4.
   
 
 0.496
fosl2
FOS-like 2, AP-1 transcription factor subunit.
    
 
 0.481
insb
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.472
neurog3
Neurog3 protein.
    
 
 0.460
LOC108181664
Hyaluronidase.
      
 0.457
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (36%) [HD]