STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itpr1aInositol 1,4,5-triphosphate receptor, type 1a (2727 aa)    
Predicted Functional Partners:
ahcyl1
Adenosylhomocysteinase; S-adenosylhomocysteine hydrolase-like 1
    
 0.946
stim1a
Stromal interaction molecule 1a
    
 0.944
stim1b
Stromal interaction molecule 1b
    
 0.944
mrvi1
Murine retrovirus integration site 1 homolog
    
 0.944
ENSDARG00000044537
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases
   
 0.935
prkg1a
Protein kinase, cGMP-dependent, type Ib
   
 0.929
calml4a
Calmodulin-like 4a
   
 0.928
prkg2
Protein kinase, cGMP-dependent, type II
   
 0.924
itpr1
Inositol 1,4,5-trisphosphate receptor, type 1
     
 
0.900
itpr3
Inositol 1,4,5-triphosphate receptor, type 3
     
 
0.900
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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