node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bach1a | emp2 | ENSDARP00000127728 | ENSDARP00000065494 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 a. | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | 0.540 |
bach1a | garem | ENSDARP00000127728 | ENSDARP00000024393 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 a. | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). | 0.838 |
bach1a | zgpat | ENSDARP00000127728 | ENSDARP00000030077 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 a. | Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration (By similarity). | 0.646 |
cav1 | emp2 | ENSDARP00000141857 | ENSDARP00000065494 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | 0.554 |
emp2 | bach1a | ENSDARP00000065494 | ENSDARP00000127728 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | BTB and CNC homology 1, basic leucine zipper transcription factor 1 a. | 0.540 |
emp2 | cav1 | ENSDARP00000065494 | ENSDARP00000141857 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.554 |
emp2 | garem | ENSDARP00000065494 | ENSDARP00000024393 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). | 0.807 |
emp2 | hsbp1b | ENSDARP00000065494 | ENSDARP00000061434 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Heat shock factor-binding protein 1b. | 0.580 |
emp2 | itsn1 | ENSDARP00000065494 | ENSDARP00000115952 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Intersectin 1 (SH3 domain protein). | 0.600 |
emp2 | itsn2a | ENSDARP00000065494 | ENSDARP00000062779 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Intersectin 2a. | 0.589 |
emp2 | itsn2b | ENSDARP00000065494 | ENSDARP00000081545 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Intersectin 2b. | 0.589 |
emp2 | lpar6b | ENSDARP00000065494 | ENSDARP00000128200 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Lysophosphatidic acid receptor 6b; Belongs to the G-protein coupled receptor 1 family. | 0.740 |
emp2 | mtdha | ENSDARP00000065494 | ENSDARP00000111658 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Metadherin a. | 0.802 |
emp2 | zgpat | ENSDARP00000065494 | ENSDARP00000030077 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration (By similarity). | 0.544 |
garem | bach1a | ENSDARP00000024393 | ENSDARP00000127728 | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). | BTB and CNC homology 1, basic leucine zipper transcription factor 1 a. | 0.838 |
garem | emp2 | ENSDARP00000024393 | ENSDARP00000065494 | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | 0.807 |
garem | zgpat | ENSDARP00000024393 | ENSDARP00000030077 | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). | Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration (By similarity). | 0.872 |
hsbp1b | emp2 | ENSDARP00000061434 | ENSDARP00000065494 | Heat shock factor-binding protein 1b. | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | 0.580 |
itsn1 | emp2 | ENSDARP00000115952 | ENSDARP00000065494 | Intersectin 1 (SH3 domain protein). | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. May play a role in glomerular filtration. | 0.600 |
itsn1 | itsn2a | ENSDARP00000115952 | ENSDARP00000062779 | Intersectin 1 (SH3 domain protein). | Intersectin 2a. | 0.596 |