node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC405768 | map2k6 | ENSDARP00000065550 | ENSDARP00000143278 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | 0.654 |
LOC405768 | map2k7 | ENSDARP00000065550 | ENSDARP00000048190 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Mitogen-activated protein kinase kinase 7. | 0.956 |
LOC405768 | myd88 | ENSDARP00000065550 | ENSDARP00000020711 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | 0.794 |
LOC405768 | tab1 | ENSDARP00000065550 | ENSDARP00000053182 | Sterile alpha motif and leucine zipper-containing kinase AZK. | TGF-beta-activated kinase 1/MAP3K7-binding protein 1. | 0.826 |
LOC405768 | tab2 | ENSDARP00000065550 | ENSDARP00000019647 | Sterile alpha motif and leucine zipper-containing kinase AZK. | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development. | 0.658 |
LOC405768 | tab3 | ENSDARP00000065550 | ENSDARP00000083707 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like. | 0.663 |
LOC405768 | tnfb | ENSDARP00000065550 | ENSDARP00000010728 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Tumor necrosis factor b (TNF superfamily, member 2). | 0.690 |
LOC405768 | tnfrsf1a | ENSDARP00000065550 | ENSDARP00000011163 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Tumor necrosis factor receptor superfamily, member 1a. | 0.728 |
LOC405768 | traf6 | ENSDARP00000065550 | ENSDARP00000036715 | Sterile alpha motif and leucine zipper-containing kinase AZK. | TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. | 0.821 |
LOC405768 | zak | ENSDARP00000065550 | ENSDARP00000150033 | Sterile alpha motif and leucine zipper-containing kinase AZK. | Sterile alpha motif and leucine zipper-containing kinase AZK. | 0.901 |
map2k6 | LOC405768 | ENSDARP00000143278 | ENSDARP00000065550 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | Sterile alpha motif and leucine zipper-containing kinase AZK. | 0.654 |
map2k6 | tab1 | ENSDARP00000143278 | ENSDARP00000053182 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | TGF-beta-activated kinase 1/MAP3K7-binding protein 1. | 0.645 |
map2k6 | tab2 | ENSDARP00000143278 | ENSDARP00000019647 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development. | 0.937 |
map2k6 | tab3 | ENSDARP00000143278 | ENSDARP00000083707 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like. | 0.924 |
map2k6 | traf6 | ENSDARP00000143278 | ENSDARP00000036715 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. | 0.702 |
map2k6 | zak | ENSDARP00000143278 | ENSDARP00000150033 | Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Phosphorylation by MAP2K6 asymmetrically activates p38 on one side of the blastodisc, an event which is n [...] | Sterile alpha motif and leucine zipper-containing kinase AZK. | 0.654 |
map2k7 | LOC405768 | ENSDARP00000048190 | ENSDARP00000065550 | Mitogen-activated protein kinase kinase 7. | Sterile alpha motif and leucine zipper-containing kinase AZK. | 0.956 |
map2k7 | tab2 | ENSDARP00000048190 | ENSDARP00000019647 | Mitogen-activated protein kinase kinase 7. | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development. | 0.933 |
map2k7 | tab3 | ENSDARP00000048190 | ENSDARP00000083707 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like. | 0.919 |
map2k7 | traf6 | ENSDARP00000048190 | ENSDARP00000036715 | Mitogen-activated protein kinase kinase 7. | TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. | 0.557 |