| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ccz1 | vamp8 | ENSDARP00000073520 | ENSDARP00000032940 | Vacuolar fusion protein CCZ1 homolog. | Vesicle-associated membrane protein 8 (Endobrevin). | 0.515 |
| ccz1 | vipas39 | ENSDARP00000073520 | ENSDARP00000132081 | Vacuolar fusion protein CCZ1 homolog. | Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part vps33b. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of vps33b. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...] | 0.425 |
| ccz1 | vps11 | ENSDARP00000073520 | ENSDARP00000052786 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.990 |
| ccz1 | vps16 | ENSDARP00000073520 | ENSDARP00000078255 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.984 |
| ccz1 | vps18 | ENSDARP00000073520 | ENSDARP00000094129 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). May be involved in vesicle trafficking to the hepatocyte apical membrane and p [...] | 0.988 |
| ccz1 | vps33b | ENSDARP00000073520 | ENSDARP00000065867 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 33B; May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating vipas39. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical recycling pathway and in the maintenance of the apical- basolateral polarity (By similarity). Plays a role in bile duct development. ECO:0000250|UniProtKB:Q9H267, ; Belongs to the STXBP/unc-18/SEC1 [...] | 0.948 |
| ccz1 | vps39 | ENSDARP00000073520 | ENSDARP00000100792 | Vacuolar fusion protein CCZ1 homolog. | VPS39 subunit of HOPS complex. | 0.993 |
| ccz1 | vps41 | ENSDARP00000073520 | ENSDARP00000116849 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.972 |
| ccz1 | vps8 | ENSDARP00000073520 | ENSDARP00000117166 | Vacuolar fusion protein CCZ1 homolog. | VPS8 subunit of CORVET complex. | 0.767 |
| ccz1 | vti1a | ENSDARP00000073520 | ENSDARP00000066255 | Vacuolar fusion protein CCZ1 homolog. | Vesicle transport through interaction with t-SNAREs 1A. | 0.673 |
| vamp8 | ccz1 | ENSDARP00000032940 | ENSDARP00000073520 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar fusion protein CCZ1 homolog. | 0.515 |
| vamp8 | vps11 | ENSDARP00000032940 | ENSDARP00000052786 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.534 |
| vamp8 | vps16 | ENSDARP00000032940 | ENSDARP00000078255 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.975 |
| vamp8 | vps18 | ENSDARP00000032940 | ENSDARP00000094129 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). May be involved in vesicle trafficking to the hepatocyte apical membrane and p [...] | 0.670 |
| vamp8 | vps33b | ENSDARP00000032940 | ENSDARP00000065867 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar protein sorting-associated protein 33B; May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating vipas39. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical recycling pathway and in the maintenance of the apical- basolateral polarity (By similarity). Plays a role in bile duct development. ECO:0000250|UniProtKB:Q9H267, ; Belongs to the STXBP/unc-18/SEC1 [...] | 0.942 |
| vamp8 | vps39 | ENSDARP00000032940 | ENSDARP00000100792 | Vesicle-associated membrane protein 8 (Endobrevin). | VPS39 subunit of HOPS complex. | 0.980 |
| vamp8 | vps41 | ENSDARP00000032940 | ENSDARP00000116849 | Vesicle-associated membrane protein 8 (Endobrevin). | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.963 |
| vamp8 | vti1a | ENSDARP00000032940 | ENSDARP00000066255 | Vesicle-associated membrane protein 8 (Endobrevin). | Vesicle transport through interaction with t-SNAREs 1A. | 0.991 |
| vipas39 | ccz1 | ENSDARP00000132081 | ENSDARP00000073520 | Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part vps33b. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of vps33b. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...] | Vacuolar fusion protein CCZ1 homolog. | 0.425 |
| vipas39 | vps11 | ENSDARP00000132081 | ENSDARP00000052786 | Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part vps33b. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of vps33b. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...] | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.675 |