STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ca7Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family. (263 aa)    
Predicted Functional Partners:
afap1l1a
Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation.
      
 0.742
heatr3
HEAT repeat-containing 3.
 
    
 0.721
nxph2a
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.669
ccar1
Cell division cycle and apoptosis regulator 1.
      
 0.643
pdzrn4
PDZ domain-containing ring finger 4.
   
  
 0.624
rpf2
Ribosome production factor 2 homolog.
   
 
 0.593
brd7
Bromodomain-containing 7.
   
  
 0.579
cahz
Carbonic anhydrase; Reversible hydration of carbon dioxide.
  
  
0.546
ca2
Carbonic anhydrase II; Belongs to the alpha-carbonic anhydrase family.
  
  
0.542
mif4gdb
MIF4G domain-containing protein B; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). Belongs to the MIF4GD family.
      
 0.529
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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