Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DMWD | ENSDARP00000157149 | ENSDARP00000003663 | ENSDARP00000157149 | Zmp:0000000529. | WD_REPEATS_REGION domain-containing protein. | 0.660 |
| DMWD | usp46 | ENSDARP00000003663 | ENSDARP00000116502 | Zmp:0000000529. | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | 0.665 |
| DMWD | wdr48a | ENSDARP00000003663 | ENSDARP00000131869 | Zmp:0000000529. | WD repeat domain 48a. | 0.660 |
| DMWD | wdr48b | ENSDARP00000003663 | ENSDARP00000056247 | Zmp:0000000529. | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. | 0.660 |
| ENSDARP00000157149 | DMWD | ENSDARP00000157149 | ENSDARP00000003663 | WD_REPEATS_REGION domain-containing protein. | Zmp:0000000529. | 0.660 |
| ENSDARP00000157149 | fancd2 | ENSDARP00000157149 | ENSDARP00000070083 | WD_REPEATS_REGION domain-containing protein. | FA complementation group D2. | 0.739 |
| ENSDARP00000157149 | usp46 | ENSDARP00000157149 | ENSDARP00000116502 | WD_REPEATS_REGION domain-containing protein. | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | 0.678 |
| ENSDARP00000157149 | wdr20a | ENSDARP00000157149 | ENSDARP00000098826 | WD_REPEATS_REGION domain-containing protein. | WD repeat domain 20a. | 0.929 |
| ENSDARP00000157149 | wdr20b | ENSDARP00000157149 | ENSDARP00000122610 | WD_REPEATS_REGION domain-containing protein. | WD repeat domain 20b. | 0.635 |
| fancd2 | ENSDARP00000157149 | ENSDARP00000070083 | ENSDARP00000157149 | FA complementation group D2. | WD_REPEATS_REGION domain-containing protein. | 0.739 |
| fancd2 | usp46 | ENSDARP00000070083 | ENSDARP00000116502 | FA complementation group D2. | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | 0.819 |
| fancd2 | wdr48a | ENSDARP00000070083 | ENSDARP00000131869 | FA complementation group D2. | WD repeat domain 48a. | 0.583 |
| fancd2 | wdr48b | ENSDARP00000070083 | ENSDARP00000056247 | FA complementation group D2. | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. | 0.889 |
| josd1 | pan2 | ENSDARP00000096632 | ENSDARP00000118293 | Josephin domain-containing 1. | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | 0.573 |
| josd1 | usp46 | ENSDARP00000096632 | ENSDARP00000116502 | Josephin domain-containing 1. | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | 0.706 |
| pan2 | josd1 | ENSDARP00000118293 | ENSDARP00000096632 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | Josephin domain-containing 1. | 0.573 |
| pan2 | usp46 | ENSDARP00000118293 | ENSDARP00000116502 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | 0.693 |
| usp46 | DMWD | ENSDARP00000116502 | ENSDARP00000003663 | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | Zmp:0000000529. | 0.665 |
| usp46 | ENSDARP00000157149 | ENSDARP00000116502 | ENSDARP00000157149 | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | WD_REPEATS_REGION domain-containing protein. | 0.678 |
| usp46 | fancd2 | ENSDARP00000116502 | ENSDARP00000070083 | Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity). | FA complementation group D2. | 0.819 |
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