STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pabpn1Poly(A)-binding protein, nuclear 1. (284 aa)    
Predicted Functional Partners:
papola
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 0.987
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
  
0.936
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
0.913
pcf11
PCF11 cleavage and polyadenylation factor subunit.
   
 
 0.911
pabpn1l
PABPN1-like, cytoplasmic.
  
  
 
0.903
srsf1b
Serine/arginine-rich splicing factor 1B; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Belongs to the splicing factor SR family.
   
 0.896
papolg
Poly(A) polymerase gamma.
   
 
 0.890
srsf9
Serine and arginine-rich-splicing factor 9.
   
 0.889
srsf5b
Serine and arginine-rich-splicing factor 5b.
   
 0.887
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
   
 
 0.876
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.