node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fzd8a | gpc4 | ENSDARP00000066834 | ENSDARP00000007058 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | 0.911 |
fzd8a | ryk | ENSDARP00000066834 | ENSDARP00000073853 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Receptor-like tyrosine kinase. | 0.918 |
fzd8a | wnt11 | ENSDARP00000066834 | ENSDARP00000090653 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.937 |
fzd8a | wnt11f2 | ENSDARP00000066834 | ENSDARP00000012233 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.896 |
fzd8a | wnt3a | ENSDARP00000066834 | ENSDARP00000089165 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.900 |
fzd8a | wnt4 | ENSDARP00000066834 | ENSDARP00000095904 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-4a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development. | 0.898 |
fzd8a | wnt8-2 | ENSDARP00000066834 | ENSDARP00000119476 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.933 |
fzd8a | wnt8a | ENSDARP00000066834 | ENSDARP00000116057 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis; Belongs to the Wnt family. | 0.931 |
fzd8a | wnt8b | ENSDARP00000066834 | ENSDARP00000049623 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May play a role in the establishment of polarity in the nervous system. | 0.904 |
fzd8a | znrf3 | ENSDARP00000066834 | ENSDARP00000154288 | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | E3 ubiquitin-protein ligase znrf3; E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components. Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification (By similarity). Belongs to the ZNRF3 family. | 0.902 |
gpc4 | fzd8a | ENSDARP00000007058 | ENSDARP00000066834 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.911 |
gpc4 | wnt11 | ENSDARP00000007058 | ENSDARP00000090653 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.696 |
gpc4 | wnt11f2 | ENSDARP00000007058 | ENSDARP00000012233 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.924 |
gpc4 | wnt3a | ENSDARP00000007058 | ENSDARP00000089165 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.617 |
gpc4 | wnt4 | ENSDARP00000007058 | ENSDARP00000095904 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt-4a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development. | 0.403 |
ryk | fzd8a | ENSDARP00000073853 | ENSDARP00000066834 | Receptor-like tyrosine kinase. | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.918 |
ryk | wnt11 | ENSDARP00000073853 | ENSDARP00000090653 | Receptor-like tyrosine kinase. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.991 |
ryk | wnt11f2 | ENSDARP00000073853 | ENSDARP00000012233 | Receptor-like tyrosine kinase. | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.989 |
ryk | wnt3a | ENSDARP00000073853 | ENSDARP00000089165 | Receptor-like tyrosine kinase. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.903 |
ryk | wnt4 | ENSDARP00000073853 | ENSDARP00000095904 | Receptor-like tyrosine kinase. | Protein Wnt-4a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development. | 0.806 |