STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnfaip8l2bTumor necrosis factor, alpha-induced protein 8-like protein 2 B; Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity); Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily. (186 aa)    
Predicted Functional Partners:
slc43a3b
Solute carrier family 43 member 3b.
   
  
 0.831
plaua
Urokinase-type plasminogen activator a; Belongs to the peptidase S1 family.
      
 0.746
tmem104
Transmembrane protein 104.
      
 0.745
rgs18
Regulator of G protein-signaling 18.
   
  
 0.700
lrrc15
Leucine-rich repeat-containing 15.
   
  
 0.672
wdr78
WD repeat domain 78.
   
  
 0.669
rpf2
Ribosome production factor 2 homolog.
      
 0.559
slc7a7
Solute carrier family 7 member 7.
   
  
 0.557
grn1
Zgc:136318 protein.
   
  
 0.553
pitpnc1b
Phosphatidylinositol transfer protein cytoplasmic 1b.
   
  
 0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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