STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfatc3aNuclear factor of-activated T cells 3a. (1074 aa)    
Predicted Functional Partners:
mapk8b
Mitogen-activated protein kinase 8; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock.
    
 0.971
mapk10
Mitogen-activated protein kinase.
    
 0.971
mapk8a
Mitogen-activated protein kinase.
    
 0.971
mapk9
Mitogen-activated protein kinase.
    
 0.959
ppp3r1b
Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.
    
 0.947
ppp3r1a
Protein phosphatase 3, regulatory subunit B, alpha a.
    
 0.947
ppp3ca
Serine/threonine-protein phosphatase.
    
 0.929
ppp3cb
Serine/threonine-protein phosphatase.
    
 0.929
ppp3ccb
Serine/threonine-protein phosphatase.
    
 0.929
ppp3cca
Serine/threonine-protein phosphatase.
    
 0.929
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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