STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kcnj11Potassium inwardly-rectifying channel, subfamily J, member 11. (381 aa)    
Predicted Functional Partners:
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
 
 
 0.995
abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9.
 
 
 0.991
rapgef4
Rap guanine nucleotide exchange factor (GEF) 4.
     
 0.765
rapgef3
Rap guanine nucleotide exchange factor (GEF) 3.
     
 0.755
ins
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.748
kcnj11l-2
Potassium inwardly rectifying channel subfamily J member 11,-like.
      
 0.731
gck
Phosphotransferase.
    
 
 0.721
insb
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.719
rfx6
DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Belongs to the RFX family.
   
  
 0.673
sergef
Secretion-regulating guanine nucleotide exchange factor.
      
 0.629
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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