STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrc8abLeucine-rich repeat-containing 8 VRAC subunit Ab. (796 aa)    
Predicted Functional Partners:
lrrc8aa
Leucine-rich repeat-containing 8 VRAC subunit Aa.
  
  
0.804
ttyh3b
Protein tweety homolog 3; Probable large-conductance Ca(2+)-activated chloride channel. Belongs to the tweety family.
      
 0.747
ttyh2
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.746
best1
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
      
 0.667
csad
Cysteine sulfinic acid decarboxylase.
    
 
 0.662
ttyh1
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.626
tmppe
Transmembrane protein with metallophosphoesterase domain; Belongs to the metallophosphoesterase superfamily. LOC643853 family.
   
  
 0.620
lrrc8db
Leucine rich repeat containing 8 family, member D.
  
 
0.537
unc50
Protein unc-50 homolog; May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity); Belongs to the unc-50 family.
      
 0.527
lrrc8c
Leucine-rich repeat-containing 8 VRAC subunit C.
  
  
0.526
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.