STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspaAspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (315 aa)    
Predicted Functional Partners:
nat8l
N-acetylaspartate synthetase; May play a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. May promote dopamine uptake by regulating TNF-alpha expression (By similarity).
   
 
 0.975
asrgl1
Isoaspartyl peptidase/L-asparaginase alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.
   
 
 0.903
F1R0Q9_DANRE
Si:dkey-103j14.5.
   
 
 0.903
asns
Asparagine synthetase [glutamine-hydrolyzing].
     
 0.902
E7FA20_DANRE
Si:ch211-256m1.8.
   
 
 0.902
F1QRA1_DANRE
Amine oxidase.
    
  0.902
got1l1
Glutamic-oxaloacetic transaminase 1-like 1.
     
 0.901
got1
Aspartate aminotransferase.
     
 0.901
rimkla
Beta-citrylglutamate synthase B; Catalyzes the synthesis of beta-citryl-L-glutamate and N- acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate. Belongs to the RimK family.
     
  0.900
got2b
Aspartate aminotransferase.
   
 
  0.900
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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