| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISCU | abcb7 | ENSDARP00000051606 | ENSDARP00000085602 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.870 |
| ISCU | aco1 | ENSDARP00000051606 | ENSDARP00000045252 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | 0.777 |
| ISCU | fech | ENSDARP00000051606 | ENSDARP00000125028 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.868 |
| ISCU | fxn | ENSDARP00000051606 | ENSDARP00000115873 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Frataxin. | 0.998 |
| ISCU | glrx5 | ENSDARP00000051606 | ENSDARP00000064111 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in iron-sulfur biogenesis. Required for normal iron homeostasis. Required for normal hemoglobin biosynthesis. | 0.883 |
| ISCU | nfs1 | ENSDARP00000051606 | ENSDARP00000084180 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.999 |
| ISCU | slc25a28 | ENSDARP00000051606 | ENSDARP00000069436 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (Probable). | 0.758 |
| abcb10 | abcb7 | ENSDARP00000082438 | ENSDARP00000085602 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.617 |
| abcb10 | aco1 | ENSDARP00000082438 | ENSDARP00000045252 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | 0.491 |
| abcb10 | fech | ENSDARP00000082438 | ENSDARP00000125028 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.992 |
| abcb10 | fxn | ENSDARP00000082438 | ENSDARP00000115873 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | Frataxin. | 0.676 |
| abcb10 | glrx5 | ENSDARP00000082438 | ENSDARP00000064111 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in iron-sulfur biogenesis. Required for normal iron homeostasis. Required for normal hemoglobin biosynthesis. | 0.644 |
| abcb10 | nfs1 | ENSDARP00000082438 | ENSDARP00000084180 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.548 |
| abcb10 | slc25a28 | ENSDARP00000082438 | ENSDARP00000069436 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (Probable). | 0.918 |
| abcb10 | steap3 | ENSDARP00000082438 | ENSDARP00000122155 | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | STEAP family member 3, metalloreductase. | 0.774 |
| abcb7 | ISCU | ENSDARP00000085602 | ENSDARP00000051606 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.870 |
| abcb7 | abcb10 | ENSDARP00000085602 | ENSDARP00000082438 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | ATP-binding cassette, sub-family B (MDR/TAP), member 10. | 0.617 |
| abcb7 | aco1 | ENSDARP00000085602 | ENSDARP00000045252 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | 0.789 |
| abcb7 | fech | ENSDARP00000085602 | ENSDARP00000125028 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.958 |
| abcb7 | fxn | ENSDARP00000085602 | ENSDARP00000115873 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Frataxin. | 0.948 |