STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc35f1Solute carrier family 35 member F1. (388 aa)    
Predicted Functional Partners:
rnf207b
RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel kcnh6a/zerg, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.
      
 0.834
ccdc141
Coiled-coil domain-containing 141.
      
 0.717
gins3
GINS complex subunit 3.
      
 0.690
ankrd9
Ankyrin repeat domain 9.
    
 
 0.668
pcid2
PCI domain-containing protein 2; Belongs to the CSN12 family.
      
 0.665
setd6
N-lysine methyltransferase setd6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
      
 0.665
litaf
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation. May also contribute to the regulation of gene expression in the nucleus. Binds DNA (in vitro) and may play a synergistic role in the nucleus in regulating the expression of numerous cytokines.
      
 0.663
kcnj2a
Potassium inwardly rectifying channel subfamily J member 2a.
   
  
 0.595
gpr153
G protein-coupled receptor 153.
   
  
 0.565
mast2
Microtubule-associated serine/threonine kinase 2.
      
 0.562
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.