STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (553 aa)    
Predicted Functional Partners:
ddb1
Damage-specific DNA-binding protein 1.
    
 
 0.968
cpdp
Zgc:66475.
   
  
 0.832
lonrf1
LON peptidase N-terminal domain and ring finger 1.
      
 0.744
ccdc58
Coiled-coil domain-containing protein 58; Belongs to the CCDC58 family.
      
 0.743
xpc
Xeroderma pigmentosum, complementation group C.
   
 
 0.705
neil1
Nei endonuclease VIII-like 1.
      
 0.692
prxl2b
Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
   
  
 0.691
dclre1a
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae).
    
 
 0.670
cul4b
Cullin 4B; Belongs to the cullin family.
    
 
 0.644
cul4a
Cullin 4A; Belongs to the cullin family.
    
 
 0.644
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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