Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ctnnb1 | foxl2a | ENSDARP00000139205 | ENSDARP00000061827 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Forkhead box L2-1. | 0.501 |
| ctnnb1 | neurog1 | ENSDARP00000139205 | ENSDARP00000073024 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...] | 0.528 |
| ctnnb1 | pax2a | ENSDARP00000139205 | ENSDARP00000071466 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Paired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. | 0.599 |
| ctnnb1 | pax6a | ENSDARP00000139205 | ENSDARP00000135767 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.725 |
| ctnnb1 | pou5f3 | ENSDARP00000139205 | ENSDARP00000065816 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...] | 0.918 |
| ctnnb1 | sox19a | ENSDARP00000139205 | ENSDARP00000100683 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Transcription factor Sox-19a; Transcriptional activator. | 0.626 |
| ctnnb1 | sox2 | ENSDARP00000139205 | ENSDARP00000095266 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). | 0.945 |
| ctnnb1 | sox3 | ENSDARP00000139205 | ENSDARP00000070099 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Transcription factor Sox-3; Transcriptional activator. | 0.738 |
| foxi1 | neurog1 | ENSDARP00000133283 | ENSDARP00000073024 | Forkhead box I1. | Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...] | 0.560 |
| foxi1 | pax2a | ENSDARP00000133283 | ENSDARP00000071466 | Forkhead box I1. | Paired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. | 0.760 |
| foxi1 | sox2 | ENSDARP00000133283 | ENSDARP00000095266 | Forkhead box I1. | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). | 0.483 |
| foxi1 | sox3 | ENSDARP00000133283 | ENSDARP00000070099 | Forkhead box I1. | Transcription factor Sox-3; Transcriptional activator. | 0.713 |
| foxl2a | ctnnb1 | ENSDARP00000061827 | ENSDARP00000139205 | Forkhead box L2-1. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.501 |
| foxl2a | gsdf | ENSDARP00000061827 | ENSDARP00000149345 | Forkhead box L2-1. | Gonadal soma derived factor variant 1. | 0.950 |
| foxl2a | sox2 | ENSDARP00000061827 | ENSDARP00000095266 | Forkhead box L2-1. | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). | 0.407 |
| foxl2a | sox3 | ENSDARP00000061827 | ENSDARP00000070099 | Forkhead box L2-1. | Transcription factor Sox-3; Transcriptional activator. | 0.718 |
| gsdf | foxl2a | ENSDARP00000149345 | ENSDARP00000061827 | Gonadal soma derived factor variant 1. | Forkhead box L2-1. | 0.950 |
| gsdf | sox3 | ENSDARP00000149345 | ENSDARP00000070099 | Gonadal soma derived factor variant 1. | Transcription factor Sox-3; Transcriptional activator. | 0.807 |
| neurog1 | ctnnb1 | ENSDARP00000073024 | ENSDARP00000139205 | Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...] | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.528 |
| neurog1 | foxi1 | ENSDARP00000073024 | ENSDARP00000133283 | Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...] | Forkhead box I1. | 0.560 |
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