STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gatd1Glutamine amidotransferase-like class 1 domain-containing protein 1. (213 aa)    
Predicted Functional Partners:
ppp1r21
Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.
    
   0.843
hypk
Huntingtin-interacting protein K.
      
 0.807
kcnh7
Potassium channel, voltage-gated eag-related subfamily H, member 7.
      
 0.803
slc4a10a
Anion exchange protein.
      
 0.744
kank4
KN motif and ankyrin repeat domains 4.
      
 0.742
eps8l2
EPS8-like 2.
      
 0.707
slc25a55a
Solute carrier family 25 (Mitochondrial carrier: glutamate), member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.662
cryzl1
Crystallin, zeta (Quinone reductase)-like 1.
   
   0.595
pnpla2
Patatin-like phospholipase domain-containing 2.
      
 0.567
yes1
Tyrosine-protein kinase yes; Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis (By similarity). Required for convergent extension cell movements during gastrulation, acting with fyna via rhoa. May be required for epiboly to occur, possibly through its effects in calcium signaling. During embryonic development, phosphorylates ptk2.1/fak.
      
 0.565
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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