STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btr32Bloodthirsty-related gene family, member 32. (531 aa)    
Predicted Functional Partners:
dnlz
DNL-type zinc finger protein; May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation.
      
 0.869
ch25hl2
Cholesterol 25-hydroxylase-like protein 2; May catalyze the formation of 25-hydroxycholesterol from cholesterol.
      
 0.720
ch25hl1.2
Cholesterol 25-hydroxylase-like protein 1, member 2; May catalyze the formation of 25-hydroxycholesterol from cholesterol.
      
 0.720
ch25hl1.1
Cholesterol 25-hydroxylase-like protein 1, member 1; May catalyze the formation of 25-hydroxycholesterol from cholesterol.
      
 0.717
ch25hl3
Cholesterol 25-hydroxylase-like 3; Belongs to the sterol desaturase family.
      
 0.646
wwox
WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development. Inhibits Wnt signaling (By similarity). Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.563
ube2l3b
Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.557
ube2l3a
Ubiquitin-conjugating enzyme E2L 3a; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.557
eif4e2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
     
 0.512
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
    
 
 0.512
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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