| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aldh18a1 | lrata | ENSDARP00000137162 | ENSDARP00000054227 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Lecithin retinol acyltransferase a. | 0.472 |
| aldh18a1 | rpe65b | ENSDARP00000137162 | ENSDARP00000071014 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.475 |
| crygm5 | rpe65b | ENSDARP00000060360 | ENSDARP00000071014 | Crystallin, gamma M5; Belongs to the beta/gamma-crystallin family. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.566 |
| lrata | aldh18a1 | ENSDARP00000054227 | ENSDARP00000137162 | Lecithin retinol acyltransferase a. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.472 |
| lrata | rlbp1b | ENSDARP00000054227 | ENSDARP00000067331 | Lecithin retinol acyltransferase a. | Cellular retinaldehyde-binding protein b. | 0.662 |
| lrata | rpe65b | ENSDARP00000054227 | ENSDARP00000071014 | Lecithin retinol acyltransferase a. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.597 |
| mc1r | rpe65b | ENSDARP00000008075 | ENSDARP00000071014 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.426 |
| nfic | rpe65b | ENSDARP00000083101 | ENSDARP00000071014 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.402 |
| nfixb | rpe65b | ENSDARP00000121809 | ENSDARP00000071014 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.540 |
| rlbp1a | rpe65b | ENSDARP00000130517 | ENSDARP00000071014 | Retinaldehyde-binding protein 1a. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.563 |
| rlbp1b | lrata | ENSDARP00000067331 | ENSDARP00000054227 | Cellular retinaldehyde-binding protein b. | Lecithin retinol acyltransferase a. | 0.662 |
| rlbp1b | rpe65b | ENSDARP00000067331 | ENSDARP00000071014 | Cellular retinaldehyde-binding protein b. | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | 0.533 |
| rpe65b | aldh18a1 | ENSDARP00000071014 | ENSDARP00000137162 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.475 |
| rpe65b | crygm5 | ENSDARP00000071014 | ENSDARP00000060360 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Crystallin, gamma M5; Belongs to the beta/gamma-crystallin family. | 0.566 |
| rpe65b | lrata | ENSDARP00000071014 | ENSDARP00000054227 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Lecithin retinol acyltransferase a. | 0.597 |
| rpe65b | mc1r | ENSDARP00000071014 | ENSDARP00000008075 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.426 |
| rpe65b | nfic | ENSDARP00000071014 | ENSDARP00000083101 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.402 |
| rpe65b | nfixb | ENSDARP00000071014 | ENSDARP00000121809 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.540 |
| rpe65b | rlbp1a | ENSDARP00000071014 | ENSDARP00000130517 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Retinaldehyde-binding protein 1a. | 0.563 |
| rpe65b | rlbp1b | ENSDARP00000071014 | ENSDARP00000067331 | All-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). | Cellular retinaldehyde-binding protein b. | 0.533 |