STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hs6st1aHeparan-sulfate 6-O-sulfotransferase 1-A; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (413 aa)    
Predicted Functional Partners:
hs6st1b
Heparan-sulfate 6-O-sulfotransferase 1-B; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
  
 
0.902
hs2st1a
Heparan sulfate 2-O-sulfotransferase 1a.
    
 
 0.814
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.
   
  
 0.788
hs3st4
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.783
hs3st2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.766
prok2
Prokineticin 2.
      
 0.753
prokr1b
Putative prokineticin receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.752
extl3
Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
      
 0.749
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor; Stimulates outgrowth of olfactory axons and migration of hypophysiotropic gonadotropin-releasing hormone 3 (GnRH3) neurons. May couple NMDA-sensitive glutamate receptor signaling to the nucleus and trigger long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes.
      
 0.734
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b.
      
 0.724
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.