STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp27a1.4Cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4; Belongs to the cytochrome P450 family. (522 aa)    
Predicted Functional Partners:
cyp7a1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
0.927
cyp8b3
Cytochrome P450, family 8, subfamily B, polypeptide 3.
     
0.925
cyp7a1b
Uncharacterized protein.
  
 
0.922
cyp7b1
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
  
  
0.922
cyp8b1
Cytochrome P450, family 8, subfamily B, polypeptide 1.
     
0.902
cyp8b2
Cytochrome P450, family 8, subfamily B, polypeptide 2.
     
0.902
soat2
Sterol O-acyltransferase 2; Belongs to the membrane-bound acyltransferase family.
   
 
 0.897
dhcr7
7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
    
 0.854
dhcr24
24-dehydrocholesterol reductase.
   
 0.832
lipf
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
  
 0.810
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.