node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdt1 | mcm2 | ENSDARP00000089247 | ENSDARP00000133012 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.997 |
cdt1 | mcm3 | ENSDARP00000089247 | ENSDARP00000003671 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.997 |
cdt1 | mcm3l | ENSDARP00000089247 | ENSDARP00000054652 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.994 |
cdt1 | mcm4 | ENSDARP00000089247 | ENSDARP00000058563 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdt1 | mcm5 | ENSDARP00000089247 | ENSDARP00000018877 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdt1 | mcm6 | ENSDARP00000089247 | ENSDARP00000022256 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.998 |
cdt1 | mcm7 | ENSDARP00000089247 | ENSDARP00000132487 | Chromatin licensing and DNA replication factor 1. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
cdt1 | mcm8 | ENSDARP00000089247 | ENSDARP00000128121 | Chromatin licensing and DNA replication factor 1. | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. | 0.979 |
cdt1 | mcm9 | ENSDARP00000089247 | ENSDARP00000115879 | Chromatin licensing and DNA replication factor 1. | DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart (By similarity). | 0.990 |
cdt1 | mcmbp | ENSDARP00000089247 | ENSDARP00000130337 | Chromatin licensing and DNA replication factor 1. | Mini-chromosome maintenance complex-binding protein; Associated component of the mcm complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the mcm complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the mcm complex. Required for sister chromatid cohesion (By similarity). | 0.868 |
mcm2 | cdt1 | ENSDARP00000133012 | ENSDARP00000089247 | DNA helicase; Belongs to the MCM family. | Chromatin licensing and DNA replication factor 1. | 0.997 |
mcm2 | mcm3 | ENSDARP00000133012 | ENSDARP00000003671 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.994 |
mcm2 | mcm3l | ENSDARP00000133012 | ENSDARP00000054652 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.994 |
mcm2 | mcm4 | ENSDARP00000133012 | ENSDARP00000058563 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
mcm2 | mcm5 | ENSDARP00000133012 | ENSDARP00000018877 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
mcm2 | mcm6 | ENSDARP00000133012 | ENSDARP00000022256 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.998 |
mcm2 | mcm7 | ENSDARP00000133012 | ENSDARP00000132487 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
mcm2 | mcm8 | ENSDARP00000133012 | ENSDARP00000128121 | DNA helicase; Belongs to the MCM family. | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. | 0.946 |
mcm2 | mcm9 | ENSDARP00000133012 | ENSDARP00000115879 | DNA helicase; Belongs to the MCM family. | DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart (By similarity). | 0.540 |
mcm2 | mcmbp | ENSDARP00000133012 | ENSDARP00000130337 | DNA helicase; Belongs to the MCM family. | Mini-chromosome maintenance complex-binding protein; Associated component of the mcm complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the mcm complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the mcm complex. Required for sister chromatid cohesion (By similarity). | 0.953 |