STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
casp21Caspase 21, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (266 aa)    
Predicted Functional Partners:
birc2
Baculoviral IAP repeat-containing 2.
   
 0.950
xiap
X-linked inhibitor of apoptosis.
   
 0.939
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.931
gzm3.2
Granzyme 3, tandem duplicate 2.
    
 0.929
gzm3.4
Granzyme 3, tandem duplicate 4.
    
 0.929
gzm3.3
Granzyme 3, tandem duplicate 3; Belongs to the peptidase S1 family.
    
 0.929
gzm3
Granzyme 3, tandem duplicate 1; Belongs to the peptidase S1 family.
   
 0.928
birc5a
Baculoviral IAP repeat-containing 5a.
   
 0.926
birc5b
Baculoviral IAP repeat-containing 5b.
   
 0.926
casp22
Caspase 22, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
  
  
0.925
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.