STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prex1Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1622 aa)    
Predicted Functional Partners:
elmo2
Engulfment and cell motility 2.
      
 0.842
rac1a
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).
    
 0.838
rac2
Rac family small GTPase 2.
    
 0.812
rhogb
Ras homolog gene family, member Gb.
    
 0.771
cdc42
Cell division cycle 42.
    
 
 0.759
cdc42l2
Cell division cycle 42-like 2.
    
 0.736
Dock2
DHR-2 domain-containing protein; Belongs to the DOCK family.
   
  
 0.697
rhoj
Ras homolog family member J.
    
 0.682
rhoq
Ras homolog gene family, member Q.
    
 0.600
rac3b
Rac family small GTPase 3b.
    
 0.600
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.