STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdaCarboxypeptidase D, a. (1350 aa)    
Predicted Functional Partners:
igf2r
Cation-independent mannose 6-phosphate receptor.
   
 
 0.775
fam91a1
Protein FAM91A1; As component of the WDR11 complex may act together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.
   
  
 0.755
sort1a
Sortilin; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Belongs to the VPS10-related sortilin family. SORT1 subfamily.
   
 
 0.692
tbc1d23
TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity). Plays a role in brain development. May act as a general inhibitor of innate immunity signaling (By similarity).
      
 0.657
m6pr
Mannose-6-phosphate receptor (cation-dependent).
   
  
 0.647
pacs1a
Phosphofurin acidic cluster sorting protein 1a.
   
  
 0.618
arrb1
Arrestin, beta 1.
     
 0.612
arf1
ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.607
snx2
Sorting nexin 2.
     
 0.603
ap1s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.587
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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