STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sf3b1Splicing factor 3b, subunit 1. (1315 aa)    
Predicted Functional Partners:
sf3b6
Splicing factor 3b, subunit 6.
   
 0.999
sf3b2
Splicing factor 3b, subunit 2.
   
 0.999
sf3b5
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
    
 0.999
sf3b4
Splicing factor 3b, subunit 4.
    
 0.999
phf5a
PHD finger protein 5A.
   
 0.999
ddx42
DEAD (Asp-Glu-Ala-Asp) box helicase 42.
   
 0.999
sf3b3
Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]
   
 0.999
sf3a2
Splicing factor 3a, subunit 2.
    
 0.998
snrpa1
Small nuclear ribonucleoprotein polypeptide A.
   
 0.998
rbmx2
RNA-binding motif protein X-linked 2.
    
 0.997
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.