STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfip11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. (832 aa)    
Predicted Functional Partners:
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15.
   
 
 0.998
crnkl1
Crooked neck pre-mRNA-splicing factor 1.
   
 0.995
bud31
Protein BUD31 homolog; Involved in pre-mRNA splicing process.
   
 
 0.989
xab2
Similar to Xab2 protein.
   
 0.983
eftud2
Elongation factor Tu GTP-binding domain-containing 2.
   
 
 0.963
prpf8
Pre-mRNA-processing factor 8.
   
 
 0.953
snrpa1
Small nuclear ribonucleoprotein polypeptide A.
   
 
 0.936
snw1
SNW domain-containing 1.
   
 
 0.929
syf2
Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome.
   
  0.928
yju2
Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex ; Belongs to the CWC16 family. YJU2 subfamily.
   
 
 0.914
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.