STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arxaAristaless-related homeobox protein; Appears to be indispensable for the central nervous system development. May have a role in the neuronal differentiation of the ganglionic eminence and ventral thalamus. May also be involved in axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily. (453 aa)    
Predicted Functional Partners:
gcga
Glucagon a.
      
 0.669
sox4b
Transcription factor SOX.
   
  
 0.668
pnoca
Prepronociceptin a.
      
 0.644
gcgb
Glucagon b.
      
 0.585
A2CEM5_DANRE
Si:ch211-145o7.3.
   
 
 0.571
mdga2a
MAM domain-containing glycosylphosphatidylinositol anchor 2a.
    
 
 0.561
tafa1a
TAFA chemokine-like family member 1a.
      
 0.552
ucn3l
Novel protein similar to vertebrate urocortin 3 (Stresscopin) (UCN3).
      
 0.540
insm1b
Insulinoma-associated protein 1b; May act as a transcriptional regulator. May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
   
  
 0.517
sst2
Somatostatin 2.
      
 0.502
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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