STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
txndc17Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity); Belongs to the thioredoxin family. (123 aa)    
Predicted Functional Partners:
ndufa2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
  
 0.770
rcan1a
Regulator of calcineurin 1a.
      
 0.743
I3IS45_DANRE
Si:dkey-204a24.11.
      
 0.647
gata1b
GATA-binding protein 1b.
      
 0.644
grxcr1b
Glutaredoxin and cysteine-rich domain-containing 1 b.
      
 0.644
timm8b
Translocase of inner mitochondrial membrane 8 homolog B (Yeast); Belongs to the small Tim family.
   
    0.622
higd1a
HIG1 hypoxia-inducible domain family, member 1A.
   
  
 0.581
TXN
Thioredoxin; Belongs to the thioredoxin family.
   
  
 0.576
zdbf2
Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.
   
  
 0.568
mrpl51
39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family.
   
    0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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