STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
krt8Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. (520 aa)    
Predicted Functional Partners:
krt18a.1
Keratin, type I cytoskeletal 18; When phosphorylated, plays a role in filament reorganization.
   
0.915
ube2v1
Ubiquitin-conjugating enzyme E2 variant 1.
   
 
 0.810
cyt1
Type I cytokeratin, enveloping layer; Belongs to the intermediate filament family.
  
0.680
krt92
Keratin 92; Belongs to the intermediate filament family.
  
0.675
krt97
Keratin 97; Belongs to the intermediate filament family.
  
0.675
krt17
Si:dkeyp-113d7.7; Belongs to the intermediate filament family.
  
0.671
krt94
Keratin 94; Belongs to the intermediate filament family.
  
0.659
cdh1
Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.654
krt91
Keratin 91; Belongs to the intermediate filament family.
   
0.645
krt93
Keratin 93; Belongs to the intermediate filament family.
  
0.643
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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