node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ak9 | ctps1a | ENSDARP00000118427 | ENSDARP00000121703 | Adenylate kinase 9. | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | 0.948 |
ak9 | ctps1b | ENSDARP00000118427 | ENSDARP00000139667 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.948 |
ak9 | enpp1 | ENSDARP00000118427 | ENSDARP00000112341 | Adenylate kinase 9. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.906 |
ak9 | itpa | ENSDARP00000118427 | ENSDARP00000074674 | Adenylate kinase 9. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.947 |
ak9 | nme6 | ENSDARP00000118427 | ENSDARP00000094574 | Adenylate kinase 9. | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.950 |
ak9 | nudt2 | ENSDARP00000118427 | ENSDARP00000076102 | Adenylate kinase 9. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 2. | 0.909 |
ctps1a | ak9 | ENSDARP00000121703 | ENSDARP00000118427 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Adenylate kinase 9. | 0.948 |
ctps1a | ctps1b | ENSDARP00000121703 | ENSDARP00000139667 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.901 |
ctps1a | enpp1 | ENSDARP00000121703 | ENSDARP00000112341 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.914 |
ctps1a | itpa | ENSDARP00000121703 | ENSDARP00000074674 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.858 |
ctps1a | nme6 | ENSDARP00000121703 | ENSDARP00000094574 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.981 |
ctps1a | nudt15 | ENSDARP00000121703 | ENSDARP00000147680 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.774 |
ctps1a | nudt2 | ENSDARP00000121703 | ENSDARP00000076102 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 2. | 0.947 |
ctps1a | nudt5 | ENSDARP00000121703 | ENSDARP00000138693 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family. | 0.499 |
ctps1b | ak9 | ENSDARP00000139667 | ENSDARP00000118427 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Adenylate kinase 9. | 0.948 |
ctps1b | ctps1a | ENSDARP00000139667 | ENSDARP00000121703 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | 0.901 |
ctps1b | enpp1 | ENSDARP00000139667 | ENSDARP00000112341 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.907 |
ctps1b | itpa | ENSDARP00000139667 | ENSDARP00000074674 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.858 |
ctps1b | nme6 | ENSDARP00000139667 | ENSDARP00000094574 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.949 |
ctps1b | nudt15 | ENSDARP00000139667 | ENSDARP00000147680 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.774 |