STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdx1Peroxiredoxin 1. (199 aa)    
Predicted Functional Partners:
srxn1
Sulfiredoxin.
   
 0.956
TXN
Thioredoxin; Belongs to the thioredoxin family.
  
 0.936
prdx2
Peroxiredoxin 2.
  
 
 
0.901
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.900
txn
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.880
gstp1
Pi-class glutathione S-transferase; Belongs to the GST superfamily.
   
 
 0.850
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
  
 0.807
gsr
Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.766
sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.765
erp44
Thioredoxin domain containing 4 (Endoplasmic reticulum).
  
 
 0.746
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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