STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (468 aa)    
Predicted Functional Partners:
icmt
Protein-S-isoprenylcysteine O-methyltransferase.
   
 0.988
fnta
Farnesyltransferase, CAAX box, alpha.
   
 
 0.954
fntb
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
     
 0.937
rce1a
Ras-converting CAAX endopeptidase 1a.
    
 
 0.933
rce1b
Ras-converting CAAX endopeptidase 1b.
    
 
 0.933
lmna
Lamin A; Belongs to the intermediate filament family.
   
 
 0.858
MSANTD2
Si:ch211-80m8.2.
      
 0.717
grpel1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.603
grpel2
GrpE-like 2, mitochondrial; Belongs to the GrpE family.
  
  
 0.603
dars2
Aspartyl-tRNA synthetase 2, mitochondrial.
  
  
 0.564
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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