STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgap36Rho GTPase-activating protein 36. (630 aa)    
Predicted Functional Partners:
rhbdl1
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
      
 0.837
unc50
Protein unc-50 homolog; May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity); Belongs to the unc-50 family.
      
 0.834
wdr90
WD repeat domain 90.
      
 0.745
akap17a
A kinase (PRKA) anchor protein 17A.
      
 0.697
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.674
nek10
NIMA-related kinase 10.
      
 0.667
aspm
Abnormal spindle microtubule assembly.
   
 
 0.666
slc38a6
Probable sodium-coupled neutral amino acid transporter 6; Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate. Belongs to the amino acid/polyamine transporter 2 family.
      
 0.663
ttk
Dual specificity protein kinase Ttk; Phosphorylates proteins on serine, threonine, and tyrosine (By similarity). Involved in mitotic cell cycle checkpoint control. Required for fin and heart regeneration. Required to prevent chromosome segregation errors during meiosis. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
    0.619
vwc2
Von Willebrand factor C domain-containing 2.
      
 0.599
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.