STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfklaATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)    
Predicted Functional Partners:
hkdc1
Hexokinase domain-containing 1.
   
 
 0.992
hk1
Hexokinase 1.
   
 
 0.992
hk2
Hexokinase 2.
   
 
 0.992
gpia
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.985
fbp1a
Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.
    
 0.982
gpib
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.982
taldo1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.976
fbp1b
Fructose-1,6-bisphosphatase 1b; Belongs to the FBPase class 1 family.
    
 0.972
tktb
Transketolase b.
  
 
 0.967
tkta
Transketolase a.
  
 
 0.966
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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