STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eva1aProtein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis; Belongs to the EVA1 family. (153 aa)    
Predicted Functional Partners:
nefmb
Neurofilament, medium polypeptide b; Belongs to the intermediate filament family.
      
 0.868
layna
Layilin a.
      
 0.839
E7F569_DANRE
Si:ch211-153b23.5.
      
 0.839
ENSDARP00000135027
Si:ch73-335m24.2.
 
      0.836
F1QX88_DANRE
Si:ch211-51a6.2; Belongs to the peptidase S1 family.
   
  
 0.831
smoc1
SPARC-related modular calcium-binding 1.
      
 0.731
es1
ES1 protein, mitochondrial; Plays a role in promoting mitochondrial enlargement in cone photoreceptor cells in a fusion-independent and ATP-dependent manner.
      
 0.667
prss12
Serine protease 12; Belongs to the peptidase S1 family.
      
 0.566
atg9a
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.563
agbl5
Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains.
      
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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