STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foxo1bForkhead box protein O1-B; Transcriptional regulator of cell cycle arrest required for cellular stress responses. (629 aa)    
Predicted Functional Partners:
akt3a
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.958
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.954
akt2l
V-akt murine thymoma viral oncogene homolog 2,-like.
   
 0.948
akt3b
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.947
akt1
Non-specific serine/threonine protein kinase.
    
 0.947
usp7
Ubiquitin-specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
   
 0.932
stat3
Signal transducer and activator of transcription.
   
 0.928
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.923
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.922
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.922
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.