STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
march2E3 ubiquitin-protein ligase MARCHF2; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. (249 aa)    
Predicted Functional Partners:
stx6
Stx6 protein; Belongs to the syntaxin family.
    
 
 0.766
smox
Spermine oxidase.
   
  
 0.740
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 
 0.723
pdzk1ip1
PDZK1-interacting protein 1.
   
  
 0.707
rnf145b
RING finger protein 145.
    
 
 0.671
fbxo28
F-box protein 28.
   
    0.629
F8W2F5_DANRE
Si:dkey-22i16.9.
      
 0.629
pttg1ipb
Pituitary tumor-transforming 1 interacting protein.
      
 0.619
cnot2
CCR4-NOT transcription complex, subunit 2.
    
 
 0.613
E7EZJ4_DANRE
Si:dkey-42l23.7.
      
 0.584
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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