STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prss12Serine protease 12; Belongs to the peptidase S1 family. (816 aa)    
Predicted Functional Partners:
agrn
Agrin.
   
 
 0.760
myo9ab
Unconventional myosin-IXAb; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons (By similarity). Required for the regulation of neurite branching and motor neuron axon guidance.
      
 0.733
LOC563933
Serine protease; Belongs to the peptidase S1B family.
      
 0.669
scoca
Short coiled-coil protein A; Positive regulator of amino acid starvation-induced autophagy; Belongs to the SCOC family.
      
 0.669
myo9aa
Unconventional myosin-IXAa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons (By similarity). Required for the regulation of neurite branching and motor neuron axon guidance.
      
 0.661
musk
Muscle, skeletal, receptor tyrosine kinase.
    
 
 0.607
grhprb
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  
 0.571
eva1a
Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis; Belongs to the EVA1 family.
      
 0.566
EVA1A
Eva-1 homolog A, regulator of programmed cell death.
      
 0.566
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3.
      
 0.545
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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