STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sema6bbSema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb. (639 aa)    
Predicted Functional Partners:
plxna2
Plexin A2.
   
 
 0.797
plxnb3
Plexin B3.
    
 
 0.722
dpysl4
Dihydropyrimidinase-like 4.
      
 0.660
epha6
Eph receptor A6.
   
 
 0.580
dpysl3
Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
      
 0.555
ephb6
Receptor protein-tyrosine kinase.
   
 
 0.542
plxnb2b
Plexin b2b.
   
 
0.532
plxnb2a
Plexin b2a.
    
 
0.503
plxnb1a
Plexin b1a.
    
 
0.502
plxnb1b
Plexin b1b.
    
 
0.496
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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