node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acacb | acat1 | ENSDARP00000083511 | ENSDARP00000133230 | Acetyl-CoA carboxylase beta. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.947 |
acacb | acat2 | ENSDARP00000083511 | ENSDARP00000018064 | Acetyl-CoA carboxylase beta. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.943 |
acacb | acss1 | ENSDARP00000083511 | ENSDARP00000044327 | Acetyl-CoA carboxylase beta. | Acetyl-coenzyme A synthetase. | 0.949 |
acacb | acss2 | ENSDARP00000083511 | ENSDARP00000055053 | Acetyl-CoA carboxylase beta. | Acetyl-coenzyme A synthetase. | 0.944 |
acacb | cpt1aa | ENSDARP00000083511 | ENSDARP00000077866 | Acetyl-CoA carboxylase beta. | Carnitine palmitoyltransferase 1Aa (liver); Belongs to the carnitine/choline acetyltransferase family. | 0.960 |
acacb | cpt1b | ENSDARP00000083511 | ENSDARP00000077856 | Acetyl-CoA carboxylase beta. | Carnitine palmitoyltransferase 1B (muscle). | 0.947 |
acacb | fasn | ENSDARP00000083511 | ENSDARP00000112100 | Acetyl-CoA carboxylase beta. | Coiled-coil domain containing 57. | 0.974 |
acacb | mcat | ENSDARP00000083511 | ENSDARP00000005503 | Acetyl-CoA carboxylase beta. | Malonyl CoA:ACP acyltransferase (mitochondrial). | 0.949 |
acacb | prkaa1 | ENSDARP00000083511 | ENSDARP00000079966 | Acetyl-CoA carboxylase beta. | Non-specific serine/threonine protein kinase. | 0.929 |
acacb | prkaa2 | ENSDARP00000083511 | ENSDARP00000080103 | Acetyl-CoA carboxylase beta. | Non-specific serine/threonine protein kinase. | 0.946 |
acat1 | acacb | ENSDARP00000133230 | ENSDARP00000083511 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-CoA carboxylase beta. | 0.947 |
acat1 | acat2 | ENSDARP00000133230 | ENSDARP00000018064 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.904 |
acat1 | acss1 | ENSDARP00000133230 | ENSDARP00000044327 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-coenzyme A synthetase. | 0.969 |
acat1 | acss2 | ENSDARP00000133230 | ENSDARP00000055053 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-coenzyme A synthetase. | 0.965 |
acat1 | cpt1aa | ENSDARP00000133230 | ENSDARP00000077866 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Carnitine palmitoyltransferase 1Aa (liver); Belongs to the carnitine/choline acetyltransferase family. | 0.410 |
acat1 | fasn | ENSDARP00000133230 | ENSDARP00000112100 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Coiled-coil domain containing 57. | 0.576 |
acat2 | acacb | ENSDARP00000018064 | ENSDARP00000083511 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA carboxylase beta. | 0.943 |
acat2 | acat1 | ENSDARP00000018064 | ENSDARP00000133230 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.904 |
acat2 | acss1 | ENSDARP00000018064 | ENSDARP00000044327 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase. | 0.956 |
acat2 | acss2 | ENSDARP00000018064 | ENSDARP00000055053 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase. | 0.956 |