STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cacna1eCalcium channel, voltage-dependent, R type, alpha 1E subunit a. (1793 aa)    
Predicted Functional Partners:
CACNA2D1
Si:dkey-266j7.2.
   
 0.841
cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
   
 0.764
cacng1b
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.759
naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit.
      
 0.742
cacng1a
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.734
rasgrp3
RAS guanyl-releasing protein 3 (calcium and DAG-regulated).
   
 
 0.687
cacnb4a
Voltage-gated calcium channel beta-4 subunit variant 2.
   
 0.672
cacnb3a
Calcium channel, voltage-dependent, beta 3a.
   
 0.672
cacnb4b
Voltage-gated calcium channel beta-4 subunit variant 2.
   
 0.672
cacnb2b
Voltage-dependent calcium channel beta 2a subunit.
   
 0.672
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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