STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyb5r2NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (309 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
 
 
  
 0.969
umps
Uridine monophosphate synthetase.
  
 
 0.932
cyb5a
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
 
 0.918
cyb5b
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
 
 0.917
cmah
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
   
 0.904
dhodh
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.896
dpydb
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity); Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.865
dpyda.1
Dihydropyrimidine dehydrogenase a, tandem duplicate 1.
  
 0.864
dpyda.1-2
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.864
zgc:77112
Protein phosphatase 1 regulatory subunit.
      
 0.806
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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