STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rspry1Ring finger and SPRY domain-containing 1. (580 aa)    
Predicted Functional Partners:
arl2bp
ADP-ribosylation factor-like protein 2-binding protein; Plays a role as an effector of the ADP-ribosylation factor- like protein 2, ARL2; Belongs to the ARL2BP family.
 
    
 0.917
gpatch3
G patch domain-containing 3.
      
 0.872
eaf1
ELL-associated factor 1.
      
 0.869
znrf2b
E3 ubiquitin-protein ligase znrf2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
      
 0.864
plekha8
Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN) to the plasma membrane.
      
 0.857
ggctb
Gamma-glutamylcyclotransferase b.
      
 0.825
efcab1
EF-hand calcium-binding domain 1.
      
 0.824
fkbp14
Peptidylprolyl isomerase.
      
 0.789
mettl6
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
   
  
 0.776
snx20
Sorting nexin 20.
      
 0.760
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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