STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brat1BRCA1-associated ATM activator 1; Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. (822 aa)    
Predicted Functional Partners:
brap
BRCA1-associated protein.
   
  
 0.735
pag1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
      
 0.735
e4f1
Transcription factor E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase. Functions in cell survival and proliferation through control of the cell cycle.
   
    0.657
tubgcp4
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.614
nsmce2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
      
 0.585
bbx
BBX high mobility group box domain-containing.
      
 0.564
trmt10a
tRNA methyltransferase 10A.
   
  
 0.555
tubgcp6
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2.
      
 0.545
ier3ip1
Immediate early response 3-interacting protein 1; May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family.
      
 0.540
ralba
V-ral simian leukemia viral oncogene homolog Ba (ras-related).
      
 0.512
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (36%) [HD]