node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
leo1 | polr2c | ENSDARP00000072160 | ENSDARP00000043811 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide C. | 0.994 |
leo1 | polr2d | ENSDARP00000072160 | ENSDARP00000099022 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide D. | 0.992 |
leo1 | polr2f | ENSDARP00000072160 | ENSDARP00000053200 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide F. | 0.993 |
leo1 | polr2gl | ENSDARP00000072160 | ENSDARP00000073018 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems [...] | 0.992 |
leo1 | polr2h | ENSDARP00000072160 | ENSDARP00000056187 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. | 0.992 |
leo1 | polr2i | ENSDARP00000072160 | ENSDARP00000059195 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.994 |
leo1 | polr2j | ENSDARP00000072160 | ENSDARP00000050901 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide J. | 0.993 |
leo1 | polr2k | ENSDARP00000072160 | ENSDARP00000099037 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.992 |
leo1 | polr2l | ENSDARP00000072160 | ENSDARP00000075655 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Polymerase (RNA) II (DNA directed) polypeptide L. | 0.992 |
leo1 | tceanc2 | ENSDARP00000072160 | ENSDARP00000085930 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | Transcription elongation factor A N-terminal and central domain-containing protein 2. | 0.862 |
polr2c | leo1 | ENSDARP00000043811 | ENSDARP00000072160 | Polymerase (RNA) II (DNA directed) polypeptide C. | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development. | 0.994 |
polr2c | polr2d | ENSDARP00000043811 | ENSDARP00000099022 | Polymerase (RNA) II (DNA directed) polypeptide C. | Polymerase (RNA) II (DNA directed) polypeptide D. | 0.999 |
polr2c | polr2f | ENSDARP00000043811 | ENSDARP00000053200 | Polymerase (RNA) II (DNA directed) polypeptide C. | Polymerase (RNA) II (DNA directed) polypeptide F. | 0.999 |
polr2c | polr2gl | ENSDARP00000043811 | ENSDARP00000073018 | Polymerase (RNA) II (DNA directed) polypeptide C. | DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems [...] | 0.999 |
polr2c | polr2h | ENSDARP00000043811 | ENSDARP00000056187 | Polymerase (RNA) II (DNA directed) polypeptide C. | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. | 0.999 |
polr2c | polr2i | ENSDARP00000043811 | ENSDARP00000059195 | Polymerase (RNA) II (DNA directed) polypeptide C. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.999 |
polr2c | polr2j | ENSDARP00000043811 | ENSDARP00000050901 | Polymerase (RNA) II (DNA directed) polypeptide C. | Polymerase (RNA) II (DNA directed) polypeptide J. | 0.999 |
polr2c | polr2k | ENSDARP00000043811 | ENSDARP00000099037 | Polymerase (RNA) II (DNA directed) polypeptide C. | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.999 |
polr2c | polr2l | ENSDARP00000043811 | ENSDARP00000075655 | Polymerase (RNA) II (DNA directed) polypeptide C. | Polymerase (RNA) II (DNA directed) polypeptide L. | 0.999 |
polr2c | tceanc2 | ENSDARP00000043811 | ENSDARP00000085930 | Polymerase (RNA) II (DNA directed) polypeptide C. | Transcription elongation factor A N-terminal and central domain-containing protein 2. | 0.820 |