STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bap1Ubiquitin carboxyl-terminal hydrolase BAP1; Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity). (755 aa)    
Predicted Functional Partners:
asxl2
ASXL transcriptional regulator 2.
    
 0.997
asxl1
ASXL transcriptional regulator 1.
   
 0.980
bard1
BRCA1-associated RING domain 1.
    
 0.964
hcfc1b
Host cell factor C1b.
    
 0.962
usp14
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.955
adrm1
Proteasomal ubiquitin receptor ADRM1; Functions as a proteasomal ubiquitin receptor. Promotes the deubiquitinating activity associated with the 26S proteasome (By similarity); Belongs to the ADRM1 family.
   
 
 0.942
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.938
psmd8
Proteasome 26S subunit, non-ATPase 8.
   
 
 0.935
psmd7
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog).
   
 
 0.931
psma1
Proteasome subunit alpha type.
   
 
 0.914
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.